#5 Is a Testosterone Level of 450 Actually Low?

Got a testosterone result of 450 and an offer to start TRT? Before you say yes, here’s what the Endocrine Society actually requires for a diagnosis: real symptoms plus a level that’s confirmed low on repeat morning testing. Dr. Remina breaks down the conditions that should stop a prescription, what the TRAVERSE trial found about testosterone and heart health, why chasing a higher number isn’t automatically better, and which labs to ask for before treatment and once you’re on it.

Source:

Bhasin S, et al., “Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline.” J Clin Endocrinol Metab, 2018.

https://pubmed.ncbi.nlm.nih.gov/29562364/

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Timestamps

00:00 - Introduction: Is testosterone 450 low?

01:03 - Endocrine Society TRT diagnosis guidelines

02:20 - Guidelines vs. real-world TRT prescribing

03:34 - Who shouldn't start testosterone therapy

05:12 - TRAVERSE trial: TRT and heart health

05:59 - TRT side effects and FDA warnings

06:51 - Genetics, testosterone, and longevity optimizing

08:24 - How to test for low testosterone

09:01 - Monitoring labs once you're on TRT

09:27 - Who TRT actually helps

Disclaimer: This show is medical education, not medical advice. I'm sharing general information to help you understand your body, and listening doesn't create a physician-patient relationship between us. Everyone is different, so please talk with your own physician before you make changes to your health care.